Whole genome comparison using Pairwise FLAG
Kung-Hao Liang, Ph. D.
Department of Bioinformatics, Molecular Biomedical Technology Division,
Biomedical Engineering Center,
Industrial Technology Research Institute,
7F, Building 53,
195 Section 4, Chung-Hsing Road,
Chutung, Hsin-Chu 310, Taiwan, R.O.C.
Whole genome comparison can provide great insight
into many aspects of biology. Pairwise FLAG, a bioinformatics
software developed in ITRI, is designed for pairwise local
alignment of nucleotide sequences. Compared with BLAST,
FLAG is advantageous due to its speed and sensitivity. Therefore,
Pairwise FLAG is especially suitable for whole genome comparison.
In this talk, I will introduce Pairwise FLAG and
show how it can lead to new biological discoveries.